White Paper

Tracing the propagation of aerosol with Biotagging

Reply’s experiment based on Advanced Traceability simulates the spread dynamics of COVID-19’s main transmission vehicle in enclosed spaces

Biotagging: a game-changer in airflow tracing

Biotagging is the use of DNA-based marker (and other chemicals) that can be applied to substances to enable their traceability. With no genetic alterations involved, the Biotag carries complex data capable of ensuring its uniqueness.


The use of Biotagging technologies to detect and simulate the dynamics of aerosol (tiny breath droplets that can carry pathogens in the air) is a game-changer in the fight against COVID-19. That’s because it allows us to understand how these particles move within a shared indoor space such as an office, a school, a production plant or a hospital.

By diluting a Biotag in a special liquid and spraying it in a closed space, the traceable marker will mimic the movement of the droplets capable of transmitting the virus. Thanks to this technology, it is thus possible to help risk managers to reassess the configuration of systems, spaces and procedures, to reduce the possibility of contagion.

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Understand the internal airflow within diverse HVAC scenarios.



Optimise procedures and the occupancy of classrooms.



Isolate internal sectors according to risk and vulnerability.


Improve worker's safety across every stage of the production.